The 3<sup>rd</sup> International Conference on Drug Discovery & Therapy: Dubai, February 7 - 11, 2011

Pharmaceutical Research & Development (Track)

Cardiac neurons firing precedes cortical neurons firing by variable time equivalent to RP or Lipet`s latency period in goal directed behavior or action in conscious state

Amna Alfaki
Omdurman Islamic University , Department of Pediatrics


Abstract:

The signals, and the neuronal mechanisms that underlying the behavior, actions and action–directed goals in man and animals during conscious state is not fully understood, as well as the neuro-dynamic mechanisms and the source of these neuronal signals are not authenticated.Temporal judgment alone can neither account for neural signaling necessary for emergence of conscious act nor can explain the readiness potential RP (the accepted neural correlate time needed for the neurons to fire)  that precede the onset of action or  the  latency time of 0.5 ms that precede the  conscious act found by Lipet. Neuronal feedback mechanisms between the heart and the brain seem feasible and logical suggestions to be considered, so clearly I would suggest that the onset of a conscious directed goal, conscious action, freewill, and intension, the neural signals and mechanisms that control them may depend upon the interaction between two sources:

1) Brain, 2)Heart.  The- temporal –cardiac (neural system )  interaction has been well established in the  heart-brain interaction studies by many workers w ho  found that the work of the heart precede that of the brain in EEG findings in conscious stimulation, which may explain and  account for RP time and the 0.5 ms latency period of Lipet`s important findings. According to my hypothesis(AlFaki,2009)and views  the  temporal neurons in the somato-sensory cortex will respond to conscious stimulation only after receiving neuronal signals from the  cardiac neurons in the neural plexus of the  heart, after variable millisecond equivalent (RP) or Lipet’s latency period prior to temporal neuronal fringing in response to conscious act, this time is the time needed by cardiac neurons to process and signal information  to the brain through feedback mechanism and heart-brain interaction. Key words: Feedback mechanisms, Latency period, RP, freewill, intension,   consciousness cognition, neural plexus, heart –brain interaction